BALANCING RISKS OF BLEEDING AND STENT THROMBOSIS: A DECISION ANALYTIC MODEL TO COMPARE DURATION OF DUAL ANTIPLATELET THERAPY AFTER DRUG-ELUTING STENTS
نویسندگان
چکیده
منابع مشابه
Simultaneous Thrombosis of Two Drug-Eluting Stents After Discontinuation of Dual Antiplatelet Therapy for a Day
Stent thrombosis is rare but can lead to potential severe consequence. The incidence is relative higher in drug-eluting sent than bare-metal stent implantation. Dual antiplatelet therapy is the major treatment to avoid early and late stent thrombosis. Simultaneous two stents thrombosis is rare. Although mechanical or/and procedure factors may predispose to stent thrombosis occurred, simultaneou...
متن کاملOptimal duration of dual antiplatelet therapy after drug eluting stent implantation: a network meta-analysis
OBJECTIVE There has been much debate regarding the optimal duration of dual antiplatelet therapy (DAPT) cover after drug eluting stent (DES) implantation. We aimed to assess the relative benefits of shorter and longer durations of DAPT coverage. METHODS We performed a network meta-analysis (NMA) of all the randomized clinical trials (RCT) comparing different time durations of DAPT cover. RE...
متن کاملDuration of dual antiplatelet therapy after implantation of drug-eluting stents.
BACKGROUND The potential benefits and risks of the use of dual antiplatelet therapy beyond a 12-month period in patients receiving drug-eluting stents have not been clearly established. METHODS In two trials, we randomly assigned a total of 2701 patients who had received drug-eluting stents and had been free of major adverse cardiac or cerebrovascular events and major bleeding for a period of...
متن کاملOptimizing the Duration of Dual Antiplatelet Therapy After Implantation of Drug-eluting Coronary Stents
Editorial Percutaneous coronary intervention (PCI) with implantation of drug‑eluting stents (DESs) has become the standard of care for coronary artery disease and gives a great impetus to device industry. In 2013, approximately half million patients with coronary artery disease underwent PCI in China, with a penetration rate of DES reaching beyond 95%. The use of DES including domestic ones is ...
متن کاملOptimal duration of dual antiplatelet therapy after drug-eluting stent implantation: a randomized, controlled trial.
BACKGROUND The risks and benefits of long-term dual antiplatelet therapy remain unclear. METHODS AND RESULTS This prospective, multicenter, open-label, randomized comparison trial was conducted in 24 clinical centers in Korea. In total, 5045 patients who received drug-eluting stents and were free of major adverse cardiovascular events and major bleeding for at least 12 months after stent plac...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2014
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(14)60204-7